While NAD+ supplements are generally safe, there are some interactions to be aware of.
Known Interactions
Medications
| Medication | Interaction | Risk Level |
|---|---|---|
| Blood thinners | Theoretical increased bleeding risk | Low |
| Diabetes medications | May affect blood sugar | Moderate |
| Chemotherapy | May affect cancer treatment | High (consult oncologist) |
| Photosensitizing drugs | May increase light sensitivity | Low |
Supplements
| Supplement | Interaction | Notes |
|---|---|---|
| NMN + NR | Redundant (both raise NAD+) | Safe but unnecessary |
| NMN + TMG | Complementary (TMG supports methylation) | Recommended |
| NMN + Resveratrol | Synergistic | Recommended |
| NMN + NAD+ | Redundant | Safe but unnecessary |
Safety Guidelines
Always Tell Your Doctor
Inform your healthcare provider about:
- All supplements you’re taking
- All medications
- Any health conditions
Start Low
- Begin with the lowest recommended dose
- Monitor for any adverse reactions
- Increase gradually
Monitor Biomarkers
If you’re on medications, consider monitoring:
- Blood sugar (if diabetic)
- INR (if on blood thinners)
- Liver function (general monitoring)
Who Should Be Extra Cautious
- People on multiple medications
- People with cancer
- Pregnant/breastfeeding women
- People with liver disease
- People with autoimmune conditions