NAD+ and Sleep: How It Affects Your Rest
NAD+ plays a crucial role in regulating your sleep-wake cycle. Here’s how it affects sleep and how to optimize it. NAD+’s Role in Sleep 1. Circadian Clock Regulation NAD+ levels oscillate with your circadian rhythm: Peak in the morning (active phase) Lowest at night (rest phase) This cycle regulates sleep-wake patterns 2. Sirtuin Activity SIRT1 (a sirtuin) is NAD+-dependent and: Regulates circadian gene expression Helps maintain proper sleep timing Supports sleep quality 3. Melatonin Connection NAD+ metabolism interacts with melatonin production: ...