NMN & NR Research: Latest Clinical Trials (2026)
The science behind NMN and NR is evolving rapidly. Here’s a summary of the latest clinical research. NMN Clinical Trials 2021: NMN and Insulin Sensitivity 25 postmenopausal women with prediabetes 250mg NMN for 10 weeks Result: Improved muscle insulin sensitivity Published in Science 2022: NMN and Cardiovascular Health 30 healthy adults 1000mg NMN for 12 weeks Result: Improved arterial stiffness markers Published in Frontiers in Nutrition 2023: NMN and Endurance 48 middle-aged adults 1200mg NMN for 6 weeks Result: Improved aerobic capacity Published in Journal of the International Society of Sports Nutrition 2024: NMN and Cognitive Function 60 older adults 500mg NMN for 24 weeks Result: Improved working memory and reaction time Published in GeroScience NR Clinical Trials 2017: First Long-term NR Study 140 overweight adults 1000mg NR for 12 weeks Result: NAD+ increased 60%, safe and well-tolerated Published in American Journal of Clinical Nutrition 2019: NR and Blood Pressure 120 adults with elevated blood pressure 1000mg NR for 8 weeks Result: Reduced systolic blood pressure by 5mmHg Published in Scientific Reports 2020: NR and Liver Health 80 adults with NAFLD 1000mg NR for 6 months Result: Reduced liver fat and inflammation markers Published in Hepatology 2021: NR and COVID Recovery 100 COVID patients 1000mg NR for 2 weeks Result: Faster recovery and reduced inflammatory markers Published in Clinical Nutrition Key Takeaways What We Know Both NMN and NR effectively raise NAD+ levels Both are safe and well-tolerated in humans Both show promise for cardiovascular, metabolic, and cognitive health NMN may be slightly more effective per milligram What We’re Still Learning Optimal long-term dosing Which conditions benefit most How to identify responders vs non-responders Long-term anti-aging effects in humans Related Articles NMN vs NR: Which is Better? Best NAD+ Supplements in 2026 NAD+ and Aging